A practical method of I-131 thyroid cancer therapy dose optimization using estimated effective renal clearance

A practical method of I-131 thyroid cancer therapy dose optimization using estimated effective renal clearance

Blog Article

In thyroid cancer patients with renal impairment or other complicating factors, it is important to maximize I-131 therapy efficacy while minimizing bone marrow and lung damage.We developed a web-based calculator based on a modified Snack Box Benua and Leeper method to calculate the maximum V-Neck I-131 dose to reduce the risk of these toxicities, based on the effective renal clearance of I-123 as measured from two whole-body I-123 scans, performed at 0 and 24 h post-administration.